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Capturing the dynamics of genome replication on individual ultra-long nanopore sequence reads
Replication of eukaryotic genomes is highly stochastic, making it difficult to determine the replication dynamics of individual molecules with existing methods. We now report a sequencing method for the measurement of replication fork movement on single molecules by Detecting Nucleotide Analogue sig...
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| Pubblicato in: | Nat Methods |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7617212/ https://ncbi.nlm.nih.gov/pubmed/31011185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-019-0394-y |
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