A Repurposing Programme Evaluating Transdermal Oestradiol Patches for the Treatment of Prostate Cancer Within the PATCH and STAMPEDE Trials: Current Results and Adapting Trial Design

AIMS: Androgen deprivation therapy (ADT), usually achieved with luteinising hormone releasing hormone analogues (LHRHa), is central to prostate cancer management. LHRHa reduce both testosterone and oestrogen and are associated with significant long-term toxicity. Previous use of oral oestrogens as A...

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Gepubliceerd in:Clin Oncol (R Coll Radiol)
Hoofdauteurs: Gilbert, D.C., Nankivell, M., Rush, H., Clarke, N.W., Mangar, S., Al-hasso, A., Rosen, S., Kockelbergh, R., Sundaram, S.K., Dixit, S., Laniado, M., McPhail, N., Shaheen, A., Brown, S., Gale, J., Deighan, J., Marshall, J., Duong, T., Macnair, A., Griffiths, A., Amos, C.L., Sydes, M.R., James, N.D., Parmar, M.K.B., Langley, R.E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2024
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7617162/
https://ncbi.nlm.nih.gov/pubmed/37973477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clon.2023.10.054
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