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PERfect Day: reversible and dose-dependent control of circadian time-keeping in the mouse suprachiasmatic nucleus by translational switching of PERIOD2 protein expression

The biological clock of the suprachiasmatic nucleus (SCN) orchestrates circadian (approximately daily) rhythms of behaviour and physiology that underpin health. SCN cell-autonomous time-keeping revolves around a transcriptional/translational feedback loop (TTFL) within which PERIOD (PER1,2) and CRYP...

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Detalhes bibliográficos
Publicado no:Eur J Neurosci
Main Authors: McManus, David, Patton, Andrew P., Smyllie, Nicola J., Chin, Jason W., Hastings, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2024
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7617102/
https://ncbi.nlm.nih.gov/pubmed/39300693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.16537
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