Chromosome 12p amplification in triple-negative/BRCA1-mutated breast cancer associates with emergence of docetaxel resistance and carboplatin sensitivity

Taxanes are the mainstay of treatment in triple-negative breast cancer (TNBC), with de novo and acquired resistance limiting patient survival. To investigate the genetic basis of docetaxel resistance in TNBC, exome sequencing was performed on matched TNBC patient-derived xenografts (PDX) sensitive t...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cancer Res
Main Authors: Gómez-Miragaya, Jorge, Díaz-Navarro, Ander, Tonda, Raul, Beltran, Sergi, Palomero, Luis, Palafox, Marta, Dobrolecki, Lacey E., Huang, Chen, Vasaikar, Suhas, Zhang, Bing, Wulf, Gerburg M., Collado-Sole, Alejandro, Trinidad, Eva M, Muñoz, Purificación, Paré, Laia, Prat, Aleix, Bruna, Alejandra, Caldas, Carlos, Arribas, Joaquín, Soler-Monso, María Teresa, Petit, Anna, Balmaña, Judith, Cruz, Cristina, Serra, Violeta, Pujana, Miguel Angel, Lewis, Michael T., Puente, Xose S., González-Suárez, Eva
פורמט: Artigo
שפה:Inglês
יצא לאור: 2019
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616973/
https://ncbi.nlm.nih.gov/pubmed/31213465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-3835
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