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Immunometabolic T cell failure induces multimorbidity and aging
The impact of immunometabolism on age-associated diseases remains uncertain. Here, we show that T cells with dysfunctional mitochondria act as aging accelerators. They instigate multiple age-related features, including metabolic, cognitive, physical and cardiovascular alterations, which together res...
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| Publicado no: | Science |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7616968/ https://ncbi.nlm.nih.gov/pubmed/32439659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aax0860 |
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