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Metal-Ion Modulated Structural Transformation of Amyloid-Like Dipeptide Supramolecular Self-Assembly

The misfolding of proteins and peptides potentially leads to a conformation transition from an α-helix or random coil to β-sheet-rich fibril structures, which are associated with various amyloid degenerative disorders. Inhibition of the β-sheet aggregate formation and control of the structural trans...

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Bibliographic Details
Published in:ACS Nano
Main Authors: Ji, Wei, Yuan, Chengqian, Zilberzwige-Tal, Shai, Xing, Ruirui, Chakraborty, Priyadarshi, Tao, Kai, Gilead, Sharon, Yan, Xuehai, Gazit, Ehud
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616931/
https://ncbi.nlm.nih.gov/pubmed/31181152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.9b03444
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