Abiraterone acetate plus prednisolone with or without enzalutamide for patients with metastatic prostate cancer starting androgen deprivation therapy: final results from two randomised phase 3 trials of the STAMPEDE platform protocol

BACKGROUND: Abiraterone acetate plus prednisolone (herein referred to as abiraterone) or enzalutamide added at the start of androgen deprivation therapy improves outcomes for patients with metastatic prostate cancer. Here, we aimed to evaluate long-term outcomes and test whether combining enzalutami...

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Publicado no:Lancet Oncol
Main Authors: Attard, Gerhardt, Murphy, Laura, Clarke, Noel W, Sachdeva, Ashwin, Jones, Craig, Hoyle, Alex, Cross, William, Jones, Robert J, Parker, Christopher C, Gillessen, Silke, Cook, Adrian, Brawley, Chris, Gilson, Clare, Rush, Hannah, Abdel-Aty, Hoda, Amos, Claire L, Murphy, Claire, Chowdhury, Simon, Malik, Zafar, Martin Russell, J, Parkar, Nazia, Pugh, Cheryl, Diaz-Montana, Carlos, Pezaro, Carmel, Grant, Warren, Saxby, Helen, Pedley, Ian, O’Sullivan, Joe M, Birtle, Alison, Gale, Joanna, Srihari, Narayanan, Thomas, Carys, Tanguay, Jacob, Wagstaff, John, Das, Prantik, Gray, Emma, Alzouebi, Mymoona, Parikh, Omi, Robinson, Angus, Montazeri, Amir H, Wylie, James, Zarkar, Anjali, Cathomas, Richard, Brown, Michael D, Jain, Yatin, Dearnaley, David P, Mason, Malcolm D, Gilbert, Duncan, Langley, Ruth E, Millman, Robin, Matheson, David, Sydes, Matthew R, Brown, Louise C, Parmar, Mahesh K B, James, Nicholas D
Formato: Artigo
Idioma:Inglês
Publicado em: 2023
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616864/
https://ncbi.nlm.nih.gov/pubmed/37142371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(23)00148-1
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