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Modifiable risk factors and inflammation-related proteins in polymyalgia rheumatica: genome-wide meta-analysis and Mendelian randomisation

OBJECTIVE: Polymyalgia rheumatica (PMR) is an age-related inflammatory disease of unknown cause. We aimed to identify potentially modifiable risk factors and therapeutic targets for preventing or treating PMR. METHODS: We meta-analysed genetic association data from 8,156 cases of PMR (defined using...

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Detalhes bibliográficos
Publicado no:Rheumatology (Oxford)
Main Authors: Zhao, Sizheng Steven, Mackie, Sarah L, Larsson, Susanna C, Burgess, Stephen, Yuan, Shuai
Formato: Artigo
Idioma:Inglês
Publicado em: 2024
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616751/
https://ncbi.nlm.nih.gov/pubmed/38788669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/keae308
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