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Nanoparticle Delivery to Tumours: From EPR and ATR Mechanisms to Clinical Impact

New insights into active versus passive nanoparticle tumour entry and exit mechanisms are enriching the understanding of tumour-targeted drug delivery. Here, we align the principles of the enhanced permeability and retention (EPR) and active transport and retention (ATR), and outline how their mecha...

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Pubblicato in:Nat Rev Bioeng
Autori principali: Dasgupta, Anshuman, Sofias, Alexandros Marios, Kiessling, Fabian, Lammers, Twan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2024
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616668/
https://ncbi.nlm.nih.gov/pubmed/39376248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s44222-024-00203-3
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