Viral vectors expressing group B meningococcal outer membrane proteins induce strong antibody responses but fail to induce functional bactericidal activity

OBJECTIVE: Adenoviral vectored vaccines, with the appropriate gene insert, induce cellular and antibody responses against viruses, parasites and intracellular pathogens such as Mycobacterium tuberculosis. Here we explored their capacity to induce functional antibody responses to meningococcal transm...

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Veröffentlicht in:J Infect
Hauptverfasser: Marsay, Leanne, Dold, Christina, Paterson, Gavin K., Yamaguchi, Yuko, Derrick, Jeremy P., Chan, Hannah, Feavers, Ian M., Maiden, Martin C.J., Wyllie, David, Hill, Adrian V., Pollard, Andrew J., Rollier, Christine S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2022
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616632/
https://ncbi.nlm.nih.gov/pubmed/35245584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinf.2022.02.032
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