Which patients with metastatic hormone-sensitive prostate cancer benefit from docetaxel: a systematic review and meta-analysis of individual participant data from randomised trials

BACKGROUND: Adding docetaxel to androgen deprivation therapy (ADT) improves survival in patients with metastatic, hormone-sensitive prostate cancer, but uncertainty remains about who benefits most. We therefore aimed to obtain up-to-date estimates of the overall effects of docetaxel and to assess wh...

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Vydáno v:Lancet Oncol
Hlavní autoři: Vale, Claire L, Fisher, David J, Godolphin, Peter J, Rydzewska, Larysa H, Boher, Jean-Marie, Burdett, Sarah, Chen, Yu-Hui, Clarke, Noel W, Fizazi, Karim, Gravis, Gwenaelle, James, Nicholas D, Liu, Glenn, Matheson, David, Murphy, Laura, Oldroyd, Robert E, Parmar, Mahesh K B, Rogozinska, Ewelina, Sfumato, Patrick, Sweeney, Christopher J, Sydes, Matthew R, Tombal, Bertrand, White, Ian R, Tierney, Jayne F
Médium: Artigo
Jazyk:Inglês
Vydáno: 2023
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616350/
https://ncbi.nlm.nih.gov/pubmed/37414011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(23)00230-9
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