Sustained meningeal lymphatic vessel atrophy or expansion does not alter Alzheimer’s disease-related amyloid pathology

Discovery of meningeal lymphatic vessels (LVs) in the dura mater, also known as dural LVs (dLVs) that depend on vascular endothelial growth factor C expression, has raised interest in their possible involvement in Alzheimer’s disease (AD). Here we find that in the APdE9 and 5xFAD mouse models of AD,...

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Bibliografiske detaljer
Udgivet i:Nat Cardiovasc Res
Main Authors: Antila, Salli, Chilov, Dmitri, Nurmi, Harri, Li, Zhilin, Näsi, Anni, Gotkiewicz, Maria, Sitnikova, Valeriia, Jäntti, Henna, Acosta, Natalia, Koivisto, Hennariikka, Ray, Jonathan, Keuters, Meike Hedwig, Sultan, Ibrahim, Scoyni, Flavia, Trevisan, Davide, Wojciechowski, Sara, Kaakinen, Mika, Dvořáková, Lenka, Singh, Abhishek, Jukkola, Jari, Korvenlaita, Nea, Eklund, Lauri, Koistinaho, Jari, Karaman, Sinem, Malm, Tarja, Tanila, Heikki, Alitalo, Kari
Format: Artigo
Sprog:Inglês
Udgivet: 2024
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616318/
https://ncbi.nlm.nih.gov/pubmed/39087029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s44161-024-00445-9
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