Identification of MYCN non-amplified neuroblastoma subgroups points towards molecular signatures for precision prognosis and therapy stratification

BACKGROUND: Despite the extensive study of MYCN-amplified neuroblastomas, there is a significant unmet clinical need in MYCN non-amplified cases. In particular, the extent of heterogeneity within the MYCN non-amplified population is unknown. METHODS: A total of 1566 samples from 16 datasets were ide...

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Udgivet i:Br J Cancer
Main Authors: Hu, Xiaoxiao, Zhou, Yilu, Hill, Charlotte, Chen, Kai, Cheng, Cheng, Liu, Xiaowei, Duan, Peiwen, Gu, Yaoyao, Wu, Yeming, Ewing, Rob M., Li, Zhongrong, Wu, Zhixiang, Wang, Yihua
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2024
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616008/
https://ncbi.nlm.nih.gov/pubmed/38553589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-024-02666-y
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