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Structural basis for TBP displacement from TATA box DNA by the Swi2/Snf2 ATPase Mot1

The Swi2/Snf2 family transcription regulator Mot1 uses ATP to dissociate and reallocate the TATA box binding protein TBP from and between promoters. To reveal how Mot1 removes TBP from TATA box DNA we determined cryo-electron microscopy structures that capture different states of the remodeling reac...

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Pubblicato in:Nat Struct Mol Biol
Autori principali: Woike, Stephan, Eustermann, Sebastian, Jung, James, Wenzl, Simon Josef, Hagemann, Götz, Bartho, Joseph, Lammens, Katja, Butryn, Agata, Herzog, Franz, Hopfner, Karl-Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2023
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615866/
https://ncbi.nlm.nih.gov/pubmed/37106137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-023-00966-0
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