The histone chaperone SPT2 regulates chromatin structure and function in Metazoa

Histone chaperones control nucleosome density and chromatin structure. In yeast, the H3–H4 chaperone Spt2 controls histone deposition at active genes but its roles in metazoan chromatin structure and organismal physiology are not known. Here we identify the Caenorhabditis elegans ortholog of SPT2 (C...

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Published in:Nat Struct Mol Biol
Main Authors: Saredi, Giulia, Carelli, Francesco N., Rolland, Stéphane G. M., Furlan, Giulia, Piquet, Sandra, Appert, Alex, Sanchez-Pulido, Luis, Price, Jonathan L., Alcon, Pablo, Lampersberger, Lisa, Déclais, Anne-Cécile, Ramakrishna, Navin B., Toth, Rachel, Macartney, Thomas, Alabert, Constance, Ponting, Chris P., Polo, Sophie E., Miska, Eric A., Gartner, Anton, Ahringer, Julie, Rouse, John
Format: Artigo
Language:Inglês
Published: Nature Publishing Group US 2024
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615752/
https://ncbi.nlm.nih.gov/pubmed/38238586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-023-01204-3
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