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Structure–function analysis of the equine hepacivirus 5′ untranslated region highlights the conservation of translational mechanisms across the hepaciviruses

Equine hepacivirus (EHcV) (now also classified as hepacivirus A) is the closest genetic relative to hepatitis C virus (HCV) and is proposed to have diverged from HCV within the last 1000 years. The 5′ untranslated regions (UTRs) of both HCV and EHcV exhibit internal ribosome entry site (IRES) activi...

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Bibliografische gegevens
Gepubliceerd in:J Gen Virol
Hoofdauteurs: Lattimer, Joseph, Stewart, Hazel, Locker, Nicolas, Tuplin, Andrew, Stonehouse, Nicola J., Harris, Mark
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615701/
https://ncbi.nlm.nih.gov/pubmed/31490115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.001316
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