Myeloid cell interferon secretion restricts Zika flavivirus infection of developing and malignant human neural progenitor cells

Zika Virus (ZIKV) can infect human developing brain (HDB) progenitors resulting in epidemic microcephaly, whereas analogous cellular tropism offers treatment potential for the adult brain cancer, glioblastoma (GBM). We compared productive ZIKV infection in HDB and GBM primary tissue explants that bo...

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Опубликовано в: :Neuron
Главные авторы: Bulstrode, Harry, Girdler, Gemma C, Gracia, Tannia, Aivazidis, Alexander, Moutsopoulos, Ilias, Young, Adam MH, Hancock, John, He, Xiaoling, Ridley, Katherine, Xu, Zhaoyang, Stockley, John H, Finlay, John, Hallou, Clement, Fajardo, Teodoro, Fountain, Daniel M, van Dongen, Stijn, Joannides, Alexis, Morris, Robert, Mair, Richard, Watts, Colin, Santarius, Thomas, Price, Stephen J, Hutchinson, Peter JA, Hodson, Emma J, Pollard, Steven M, Mohorianu, Irina, Barker, Roger A, Sweeney, Trevor R, Bayraktar, Omer, Gergely, Fanni, Rowitch, David H
Формат: Artigo
Язык:Inglês
Опубликовано: 2022
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615581/
https://ncbi.nlm.nih.gov/pubmed/36174572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2022.09.002
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