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Targeting KIR as a novel approach to improve CAR-NK cell function

Chimeric antigen receptor (CAR) NK cells are demonstrating promising activity in clinical trials and possess a favorable safety profile compared to CAR-T cells. The Killer cell Immunoglobulin-like Receptors (KIR) have a critical role in the control of NK cell function, and recently, this family of a...

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Detalhes bibliográficos
Publicado no:J Transl Genet Genom
Main Authors: Graham, Lara V., Fisher, Jack G., Khakoo, Salim I., Blunt, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2023
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615527/
https://ncbi.nlm.nih.gov/pubmed/38229912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20517/jtgg.2023.25
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