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Probing excited state (1)Hα chemical shifts in intrinsically disordered proteins with a triple resonance-based CEST experiment: Application to a disorder-to-order switch
Over 40 % of eukaryotic proteomes and 15 % of bacterial proteomes are predicted to be intrinsically disordered based on their amino acid sequence. Intrinsically disordered proteins (IDPs) exist as heterogeneous ensembles of interconverting conformations and pose a challenge to the structure-function...
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| Publicado en: | Methods |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2023
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7615522/ https://ncbi.nlm.nih.gov/pubmed/37607621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2023.08.009 |
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