Coupling Lipid Nanoparticle Structure and Automated Single-Particle Composition Analysis to Design Phospholipase-Responsive Nanocarriers

Lipid nanoparticles (LNPs) are versatile structures with tunable physicochemical properties that are ideally suited as a platform for vaccine delivery and RNA therapeutics. A key barrier to LNP rational design is the inability to relate composition and structure to intracellular processing and funct...

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Publicado en:Adv Mater
Main Authors: Barriga, Hanna M.G., Pence, Isaac J., Holme, Margaret N., Doutch, James J., Penders, Jelle, Nele, Valeria, Thomas, Michael R., Carroni, Marta, Stevens, Molly M.
Formato: Artigo
Idioma:Inglês
Publicado: 2022
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615489/
https://ncbi.nlm.nih.gov/pubmed/35358374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adma.202200839
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