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Pathophysiology of multiple sclerosis damage and repair: Linking cerebral hypoperfusion to the development of irreversible tissue loss in multiple sclerosis using magnetic resonance imaging

BACKGROUND AND PURPOSE: Reduced cerebral perfusion has been observed in multiple sclerosis (MS) and may contribute to tissue loss both acutely and chronically. Here, we test the hypothesis that hypoperfusion occurs in MS and relates to the presence of irreversible tissue damage. METHODS: In 91 patie...

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Detalhes bibliográficos
Publicado no:Eur J Neurol
Main Authors: Mascali, Daniele, Villani, Alessandro, Chiarelli, Antonio M., Biondetti, Emma, Lipp, Ilona, Digiovanni, Anna, Pozzilli, Valeria, Caporale, Alessandra S., Rispoli, Marianna G., Ajdinaj, Paola, D'Apolito, Maria, Grasso, Eleonora, Sensi, Stefano L., Murphy, Kevin, Tomassini, Valentina, Wise, Richard G.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2023
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615142/
https://ncbi.nlm.nih.gov/pubmed/37154298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ene.15827
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