Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses

There is increasing recognition of the prognostic significance of tumor cell MHC class II (MHC-II) expression in anti-cancer immunity. Relapse of acute myeloid leukemia (AML) following allogeneic stem cell transplantation (alloSCT) has recently been linked to MHC-II silencing in leukemic blasts; how...

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Publicado no:Cancer Cell
Main Authors: Chan, Kah Lok, Gomez, Juliana, Cardinez, Chelisa, Kumari, Nishi, Sparbier, Christina E., Lam, Enid Y.N., Yeung, Miriam M., Garciaz, Sylvain, Kuzich, James A., Ong, Doen Ming, Brown, Fiona C., Chan, Yih-Chih, Vassiliadis, Dane, Wainwright, Elanor N., Motazedian, Ali, Gillespie, Andrea, Fennell, Katie A., Lai, Junyun, House, Imran G., Macpherson, Laura, Ang, Ching-Seng, Dawson, Sarah-Jane, Beavis, Paul A., Wei, Andrew H., Burr, Marian L., Dawson, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2022
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615013/
https://ncbi.nlm.nih.gov/pubmed/36179686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2022.09.007
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