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Designing ecologically-optimised pneumococcal vaccines using population genomics

Streptococcus pneumoniae (the pneumococcus) is a common nasopharyngeal commensal that can cause invasive pneumococcal disease (IPD). Each component of current protein-polysaccharide conjugate vaccines (PCVs) generally induces immunity specific to one of the approximately 100 pneumococcal serotypes,...

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Bibliographic Details
Published in:Nat Microbiol
Main Authors: Colijn, Caroline, Corander, Jukka, Croucher, Nicholas J.
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614922/
https://ncbi.nlm.nih.gov/pubmed/32015499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-019-0651-y
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