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Initiation of phospholipomannan β-1,2 mannosylation involves Bmts with redundant activity, influences its cell wall location and regulates β-glucans homeostasis but is dispensable for Candida albicans systemic infection

Pathogenic and non-pathogenic fungi synthesize glycosphingolipids, which have a crucial role in growth and viability. Glycosphingolipids also contribute to fungal-associated pathogenesis. The opportunistic yeast pathogen Candida albicans synthesizes phospholipomannan (PLM), which is a glycosphingoli...

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Detalhes bibliográficos
Publicado no:Biochimie
Main Authors: Courjol, F., Mille, C., Hall, R., Masset, A., Aijjou, R., Gow, N., Poulain, D., Jouault, T., Fradin, C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614791/
https://ncbi.nlm.nih.gov/pubmed/26427558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2015.09.032
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