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Pathophysiology of Dyt1-Tor1a dystonia in mice is mediated by spinal neural circuit dysfunction

Dystonia, a neurological disorder defined by abnormal postures and disorganised movements, is considered to be a neural circuit disorder with dysfunction arising within and between multiple brain regions. Given that spinal neural circuits constitute the final pathway for motor control, we sought to...

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Publicado en:Sci Transl Med
Main Authors: Pocratsky, Amanda M., Nascimento, Filipe, Özyurt, M. Görkem, White, Ian J., Sullivan, Roisin, O’Callaghan, Benjamin J., Smith, Calvin C., Surana, Sunaina, Beato, Marco, Brownstone, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado: 2023
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614689/
https://ncbi.nlm.nih.gov/pubmed/37134150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.adg3904
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