Apoptotic cell fragments locally activate tingible body macrophages in the germinal center

Germinal centers (GCs) that form within lymphoid follicles during antibody responses are sites of massive cell death. Tingible body macrophages (TBMs) are tasked with apoptotic cell clearance to prevent secondary necrosis and autoimmune activation by intracellular self antigens. We show by multiple...

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Pubblicato in:Cell
Autori principali: Grootveld, Abigail K., Kyaw, Wunna, Panova, Veera, Lau, Angelica W.Y., Ashwin, Emily, Seuzaret, Guillaume, Dhenni, Rama, Bhattacharyya, Nayan Deger, Khoo, Weng Hua, Biro, Maté, Mitra, Tanmay, Meyer-Hermann, Michael, Bertolino, Patrick, Tanaka, Masato, Hume, David A., Croucher, Peter I., Brink, Robert, Nguyen, Akira, Bannard, Oliver, Phan, Tri Giang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2023
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614509/
https://ncbi.nlm.nih.gov/pubmed/36868219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2023.02.004
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