Apoptotic cell fragments locally activate tingible body macrophages in the germinal center

Germinal centers (GCs) that form within lymphoid follicles during antibody responses are sites of massive cell death. Tingible body macrophages (TBMs) are tasked with apoptotic cell clearance to prevent secondary necrosis and autoimmune activation by intracellular self antigens. We show by multiple...

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Bibliographic Details
Published in:Cell
Main Authors: Grootveld, Abigail K., Kyaw, Wunna, Panova, Veera, Lau, Angelica W.Y., Ashwin, Emily, Seuzaret, Guillaume, Dhenni, Rama, Bhattacharyya, Nayan Deger, Khoo, Weng Hua, Biro, Maté, Mitra, Tanmay, Meyer-Hermann, Michael, Bertolino, Patrick, Tanaka, Masato, Hume, David A., Croucher, Peter I., Brink, Robert, Nguyen, Akira, Bannard, Oliver, Phan, Tri Giang
Format: Artigo
Language:Inglês
Published: 2023
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614509/
https://ncbi.nlm.nih.gov/pubmed/36868219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2023.02.004
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