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Identification of prolactin receptor variants with diverse effects on receptor signalling

The prolactin receptor (PRLR) signals predominantly through the JAK2-STAT5 pathway regulating multiple physiological functions relating to fertility, lactation, and metabolism. However, the molecular pathology and role of PRLR mutations and signalling are incompletely defined, with progress hampered...

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Détails bibliographiques
Publié dans:J Mol Endocrinol
Auteurs principaux: Gorvin, Caroline M, Newey, Paul J, Thakker, Rajesh V
Format: Artigo
Langue:Inglês
Publié: Bioscientifica Ltd 2023
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614258/
https://ncbi.nlm.nih.gov/pubmed/36445946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JME-22-0164
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