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Can polygenic risk scores contribute to cost-effective cancer screening? A systematic review

PURPOSE: Polygenic risk influences susceptibility to cancer. We assessed whether polygenic risk scores could be used in conjunction with other predictors of future disease status in costeffective risk-stratified screening for cancer. METHODS: We undertook a systematic review of papers that evaluated...

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Foilsithe in:Genet Med
Main Authors: Dixon, Padraig, Keeney, Edna, Taylor, Jenny C., Wordsworth, Sarah, Martin, Richard M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2022
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614235/
https://ncbi.nlm.nih.gov/pubmed/35575786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gim.2022.04.020
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