Rapid fractionation of mitochondria from mouse liver and heart reveals in vivo metabolite compartmentation

The compartmentation and distribution of metabolites between mitochondria and the rest of the cell is a key parameter of cell signalling and pathology. Here, we have developed a rapid fractionation procedure that enables us to take mouse heart and liver from in vivo and within ~ 30 s stabilise the d...

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發表在:FEBS Lett
Main Authors: Allen, Fay M., Costa, Ana S. H., Gruszczyk, Anja V., Bates, Georgina R., Prag, Hiran A., Nikitopoulou, Efterpi, Viscomi, Carlo, Frezza, Christian, James, Andrew M., Murphy, Michael P.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2022
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614208/
https://ncbi.nlm.nih.gov/pubmed/36217875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.14511
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