ABCB1 variants and sex affect serotonin transporter occupancy in the brain

Strategies to personalize psychopharmacological treatment promise to improve efficacy and tolerability. We measured serotonin transporter occupancy immediately after infusion of the widely prescribed P-glycoprotein substrate citalopram and assessed to what extent variants of the ABCB1 gene affect dr...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Silberbauer, Leo R., Rischka, Lucas, Vraka, Chrysoula, Hartmann, Annette M., Godbersen, Godber Mathis, Philippe, Cécile, Pacher, Daniel, Nics, Lukas, Klöbl, Manfred, Unterholzner, Jakob, Stimpfl, Thomas, Wadsak, Wolfgang, Hahn, Andreas, Hacker, Marcus, Rujescu, Dan, Kasper, Siegfried, Lanzenberger, Rupert, Gryglewski, Gregor
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2022
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613909/
https://ncbi.nlm.nih.gov/pubmed/36071112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-022-01733-1
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