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Stain-free identification of cell nuclei using tomographic phase microscopy in flow cytometry

Quantitative Phase Imaging (QPI) has gained popularity in bioimaging because it can avoid the need for cell staining, which in some cases is difficult or impossible. However, as a result, QPI does not provide labelling of various specific intracellular structures. Here we show a novel computational...

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Bibliographic Details
Published in:Nat Photonics
Main Authors: Pirone, Daniele, Lim, Joowon, Merola, Francesco, Miccio, Lisa, Mugnano, Martina, Bianco, Vittorio, Cimmino, Flora, Visconte, Feliciano, Montella, Annalaura, Capasso, Mario, Iolascon, Achille, Memmolo, Pasquale, Psaltis, Demetri, Ferraro, Pietro
Format: Artigo
Language:Inglês
Published: 2022
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613862/
https://ncbi.nlm.nih.gov/pubmed/36451849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41566-022-01096-7
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