The mitochondrial enzyme FAHD1 regulates complex II activity in breast cancer cells and is indispensable for basal BT‐20 cells in vitro

The mitochondrial enzyme fumarylacetoacetate hydrolase domain‐containing protein 1 (FAHD1) was identified to be upregulated in breast cancer tissues. Here, we show that FAHD1 is indispensable for the survival of BT‐20 cells, representing the basal breast cancer cell type. A lentiviral knock‐down of...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Holzknecht, Max, Guerrero‐Navarro, Lena, Petit, Michele, Albertini, Eva, Damisch, Elisabeth, Simonini, Anna, Schmitt, Fernando, Parson, Walther, Fiegl, Heidelinde, Weiss, Alexander, Jansen‐Duerr, Pidder
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2022
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613834/
https://ncbi.nlm.nih.gov/pubmed/35962472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.14462
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