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Antibody Delivery into the Brain by Radiosensitizer Nanoparticles for Targeted Glioblastoma Therapy

BACKGROUND: Glioblastoma is the most lethal primary brain malignancy in adults. Standard of care treatment, consisting of temozolomide (TMZ) and adjuvant radiotherapy (RT), mostly does not prevent local recurrence. The inability of drugs to enter the brain, in particular antibody-based drugs and rad...

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Bibliografiske detaljer
Udgivet i:J Nanotheranostics
Main Authors: Gal, Omer, Betzer, Oshra, Rousso-Noori, Liat, Sadan, Tamar, Motiei, Menachem, Nikitin, Maxim, Friedmann-Morvinski, Dinorah, Popovtzer, Rachela, Popovtzer, Aron
Format: Artigo
Sprog:Inglês
Udgivet: 2022
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613745/
https://ncbi.nlm.nih.gov/pubmed/36324626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jnt3040012
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