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Computational analysis of the role of mechanosensitive Notch signaling in arterial adaptation to hypertension

Arteries grow and remodel in response to mechanical stimuli. Hypertension, for example, results in arterial wall thickening. Cell-cell Notch signaling between vascular smooth muscle cells (VSMCs) is known to be involved in this process, but the underlying mechanisms are still unclear. Here, we inves...

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Detalhes bibliográficos
Publicado no:J Mech Behav Biomed Mater
Main Authors: van Asten, Jordy G.M., Ristori, Tommaso, Nolan, David R., Lally, Caitríona, Baaijens, Frank P.T., Sahlgren, Cecilia M., Loerakker, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: 2022
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613661/
https://ncbi.nlm.nih.gov/pubmed/35839633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmbbm.2022.105325
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