Unsatisfactory quality of E. coli asparaginase biogenerics in India: Implications for clinical outcomes in acute lymphoblastic leukaemia

BACKGROUND: The biotherapeutic asparaginase is a cornerstone of therapy in acute lymphoblastic leukaemia (ALL). With limited access to the original native Escherichia coli-derived asparaginase (EcASNase), a variety of EcASNase biogenerics are used in low-middle-income countries (LMICs). The variable...

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Pubblicato in:Pediatr Blood Cancer
Autori principali: Sidhu, Jasmeet, Gogoi, Manash Pratim, Agarwal, Praveen, Mukherjee, Tathagata, Saha, Debparna, Bose, Priyanka, Roy, Prakriti, Phadke, Yogesh, Sonawane, Bhatu, Paul, Pritha, Saha, Vaskar, Krishnan, Shekhar
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613163/
https://ncbi.nlm.nih.gov/pubmed/33939263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.29046
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