The Effects of an IL-21 Receptor Antagonist on the Alloimmune Response in a Humanized Mouse Skin Transplant Model

BACKGROUND: Interleukin 21 (IL-21) is involved in regulating the expansion and effector function of a broad range of leukocytes, including T cells and B cells. In transplantation, the exact role of IL-21 in the process of allograft rejection is unknown. To further explore this, the aim of this study...

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Udgivet i:Transplantation
Main Authors: de Leur, Kitty, Luk, Franka, van den Bosch, Thierry P.P., Dieterich, Marjolein, van der Laan, Luc J.W., Hendriks, Rudi W., Clahsen-van Groningen, Marian C., Issa, Fadi, Baan, Carla C., Hoogduijn, Martin J.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613120/
https://ncbi.nlm.nih.gov/pubmed/31343579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000002773
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