Neuropilin-1 is a host factor for SARS-CoV-2 infection

SARS-CoV-2, the causative agent of COVID-19, uses the viral Spike (S) protein for host cell attachment and entry. The host protease furin cleaves the full-length precursor S glycoprotein into two associated polypeptides: S1 and S2. Cleavage of S generates a polybasic Arg-Arg-Ala-Arg C-terminal seque...

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Publicat a:Science
Autors principals: Daly, James L., Simonetti, Boris, Klein, Katja, Chen, Kai-En, Williamson, Maia Kavanagh, Antón-Plágaro, Carlos, Shoemark, Deborah K., Simón-Gracia, Lorena, Bauer, Michael, Hollandi, Reka, Greber, Urs F., Horvath, Peter, Sessions, Richard B., Helenius, Ari, Hiscox, Julian A., Teesalu, Tambet, Matthews, David A., Davidson, Andrew D., Collins, Brett M., Cullen, Peter J., Yamauchi, Yohei
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612957/
https://ncbi.nlm.nih.gov/pubmed/33082294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abd3072
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