Haptoglobin genotype and outcome after spontaneous intracerebral haemorrhage

OBJECTIVE: Haptoglobin is a haemoglobin-scavenging protein that binds and neutralises free haemoglobin and modulates inflammation and endothelial progenitor cell function. A HP gene copy number variation (CNV) generates HP1 and HP2 allele, the single nucleotide polymorphism rs2000999 influences thei...

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Publicat a:J Neurol Neurosurg Psychiatry
Autors principals: Hostettler, Isabel C, Morton, Matthew J, Ambler, Gareth, Kazmi, Nabila, Gaunt, Tom, Wilson, Duncan, Shakeshaft, Clare, Jäger, Hans R, Cohen, Hannah, Yousry, Tarek, Al-Shahi Salman, Rustam, Lip, Gregory YH, Brown, Martin M, Muir, Keith W, Houlden, Henry, Bulters, Diederik, Galea, Ian, Werring, David J
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612606/
https://ncbi.nlm.nih.gov/pubmed/31924654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp-2019-321774
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