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Molecular and Clinical Repercussions of GABA Transporter 1 Variants Gone Amiss: Links to Epilepsy and Developmental Spectrum Disorders

The human γ-aminobutyric acid (GABA) transporter 1 (hGAT-1) is the first member of the solute carrier 6 (SLC6) protein superfamily. GAT-1 (SLC6A1) is one of the main GABA transporters in the central nervous system. Its principal physiological role is retrieving GABA from the synapse into neurons and...

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Bibliografski detalji
Izdano u:Front Mol Biosci
Glavni autori: Fischer, Florian P., Kasture, Ameya S., Hummel, Thomas, Sucic, Sonja
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2022
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612498/
https://ncbi.nlm.nih.gov/pubmed/35295842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2022.834498
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