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Scalable One-Pot - Liquid-Phase Oligonucleotide Synthesis for Model Network Hydrogels

Solid-phase oligonucleotide synthesis (SPOS) based on phosphoramidite chemistry is currently the most widespread technique for DNA and RNA synthesis, but suffers from scalability limitations and high reagent consumption. Liquid-phase oligonucleotide synthesis (LPOS) uses soluble polymer supports and...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Creusen, Guido, Akintayo, Cecilia Oluwadunsin, Schumann, Katja, Walther, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612451/
https://ncbi.nlm.nih.gov/pubmed/32902960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c05488
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