Disruption of endocytosis through chemical inhibition of clathrin heavy chain function

Clathrin-mediated endocytosis (CME) is a highly conserved and essential cellular process in eukaryotic cells. Although classical genetics has been used to understand CME, its highly dynamic and vital nature is difficult to approach with such tools. In contrast, small molecules can acutely and revers...

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Publicado no:Nat Chem Biol
Main Authors: Dejonghe, Wim, Sharma, Isha, Denoo, Bram, De Munck, Steven, Lu, Qing, Mishev, Kiril, Bulut, Haydar, Mylle, Evelien, De Rycke, Riet, Vasileva, Mina, Savatin, Daniel V., Nerinckx, Wim, Staes, An, Drozdzecki, Andrzej, Audenaert, Dominique, Yperman, Klaas, Madder, Annemieke, Friml, Jiří, Van Damme, Daniël, Gevaert, Kris, Haucke, Volker, Savvides, Savvas N., Winne, Johan, Russinova, Eugenia
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612312/
https://ncbi.nlm.nih.gov/pubmed/31011214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-019-0262-1
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