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A Simple, RNA-Mediated Allosteric Switch Controls the Pathway to Formation of a T = 3 Viral Capsid

Using mass spectrometry we have detected both assembly intermediates and the final product, the T = 3 viral capsid, during reassembly of the RNA bacteriophage MS2. Assembly is only efficient when both types of quasiequivalent coat protein dimer seen in the final capsid are present in solution. NMR e...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Stockley, Peter G., Rolfsson, Ottar, Thompson, Gary S., Basnak, Gabriella, Francese, Simona, Stonehouse, Nicola J., Homans, Steven W., Ashcroft, Alison E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612263/
https://ncbi.nlm.nih.gov/pubmed/17434527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.03.020
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