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Estimating the influence of body mass index (BMI) on mortality using offspring BMI as an instrumental variable

OBJECTIVE: High body mass index (BMI) is an important predictor of mortality but estimating underlying causality is hampered by confounding and pre-existing disease. Here we use information from the offspring to approximate parental BMIs, with an aim to avoid biased estimation of mortality risk caus...

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Detalhes bibliográficos
Publicado no:Int J Obes (Lond)
Main Authors: Hyppönen, Elina, Carslake, David, Berry, Diane J., Power, Chris, Smith, George Davey
Formato: Artigo
Idioma:Inglês
Publicado em: 2022
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612209/
https://ncbi.nlm.nih.gov/pubmed/34497352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41366-021-00962-8
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