Hyperpolarized Carbon-13 MRI for Early Response Assessment of Neoadjuvant Chemotherapy in Breast Cancer Patients

Hyperpolarized (13)C-MRI is an emerging tool for probing tissue metabolism by measuring (13)C-label exchange between intravenously injected hyperpolarized [1–(13)C]pyruvate and endogenous tissue lactate. Here, we demonstrate that hyperpolarized (13)C-MRI can be used to detect early response to neoad...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Woitek, Ramona, McLean, Mary A., Ursprung, Stephan, Rueda, Oscar M., Manzano Garcia, Raquel, Locke, Matthew J., Beer, Lucian, Baxter, Gabrielle, Rundo, Leonardo, Provenzano, Elena, Kaggie, Joshua, Patterson, Andrew, Frary, Amy, Field-Rayner, Johanna, Papalouka, Vasiliki, Kane, Justine, Benjamin, Arnold J.V., Gill, Andrew B., Priest, Andrew N., Lewis, David Y., Russell, Roslin, Grimmer, Ashley, White, Brian, Latimer-Bowman, Beth, Patterson, Ilse, Schiller, Amy, Carmo, Bruno, Slough, Rhys, Lanz, Titus, Wason, James, Schulte, Rolf F., Chin, Suet-Feung, Graves, Martin J., Gilbert, Fiona J., Abraham, Jean E., Caldas, Carlos, Brindle, Kevin M., Sala, Evis, Gallagher, Ferdia A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for Cancer Research 2021
Assuntos:
Translational Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612070/
https://ncbi.nlm.nih.gov/pubmed/34625424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-21-1499
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