ERAP1 Controls the Autoimmune Response against Melanocytes in Psoriasis by Generating the Melanocyte Autoantigen and Regulating its Amount for HLA-C*06:02 Presentation(1)

Autoimmune diseases develop when autoantigens activate previously quiescent self-reactive lymphocytes. Gene-gene interaction between certain human leukocyte antigen (HLA)-class I risk alleles and variants of the endoplasmic reticulum aminopeptidase ERAP1 controls the risk for common immune-mediated...

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Dades bibliogràfiques
Publicat a:J Immunol
Autors principals: Arakawa, Akiko, Reeves, Emma, Vollmer, Sigrid, Arakawa, Yukiyasu, He, Mengwen, Galinski, Adrian, Stöhr, Julia, Dornmair, Klaus, James, Edward, Prinz, Jörg C.
Format: Artigo
Idioma:Inglês
Publicat: 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611875/
https://ncbi.nlm.nih.gov/pubmed/34580106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2100686
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