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An atlas of mitochondrial DNA genotype-phenotype associations in the UK Biobank

Mitochondrial genome (mtDNA) variation in common diseases has been under-explored, partly due to a lack of genotype calling and quality control procedures. Developing an at-scale workflow for mtDNA variant analyses, we show correlations between nuclear and mitochondrial genomic structures within sub...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Yonova-Doing, Ekaterina, Calabrese, Claudia, Gomez-Duran, Aurora, Schon, Katherine, Wei, Wei, Karthikeyan, Savita, Chinnery, Patrick F., Howson, Joanna M. M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611844/
https://ncbi.nlm.nih.gov/pubmed/34002094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-021-00868-1
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