Self-repair protects microtubules from their destruction by molecular motors

Microtubule instability stems from the low energy of tubulin dimer interactions, which sets the growing polymer close to its disassembly conditions. Molecular motors use ATP hydrolysis to produce mechanical work and move on microtubules. This raises the possibility that the mechanical work produced...

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Pubblicato in:Nat Mater
Autori principali: Triclin, Sarah, Inoue, Daisuke, Gaillard, Jérémie, Htet, Zaw Min, DeSantis, Morgan E., Portran, Didier, Derivery, Emmanuel, Aumeier, Charlotte, Schaedel, Laura, John, Karin, Leterrier, Christophe, Reck-Peterson, Samara L., Blanchoin, Laurent, Théry, Manuel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611741/
https://ncbi.nlm.nih.gov/pubmed/33479528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41563-020-00905-0
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