Developmental and evolutionary dynamics of cis-regulatory elements in mouse cerebellar cells**

Organ development is orchestrated by cell- and time-specific gene regulatory networks. In this study, we investigated the regulatory basis of mouse cerebellum development from early neurogenesis to adulthood. By acquiring snATAC-seq profiles for ~90,000 cells spanning eleven stages, we mapped cerebe...

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Publié dans:Science
Auteurs principaux: Sarropoulos, Ioannis, Sepp, Mari, Frömel, Robert, Leiss, Kevin, Trost, Nils, Leushkin, Evgeny, Okonechnikov, Konstantin, Joshi, Piyush, Giere, Peter, Kutscher, Lena M., Cardoso-Moreira, Margarida, Pfister, Stefan M., Kaessmann, Henrik
Format: Artigo
Langue:Inglês
Publié: 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611596/
https://ncbi.nlm.nih.gov/pubmed/34446581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abg4696
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