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Quantifying precision loss in targeted metabolomics based on mass spectrometry and non-matching internal standards
In mass spectrometry, reliable quantification requires correction for variations in ionization efficiency between samples. The preferred method is the addition of a stable isotope labeled internal standard (SIL-IS). In targeted metabolomics, a dedicated SIL-IS for each metabolite of interest may not...
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| Publicado no: | Anal Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7611570/ https://ncbi.nlm.nih.gov/pubmed/34014078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.1c00119 |
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