Developmental cell programs are co-opted in inflammatory skin disease

The skin confers biophysical and immunological protection through a complex cellular network established early in embryonic development. We profiled the transcriptomes of over 500,000 single cells from developing fetal and adult healthy human skin, and from adult skin with atopic dermatitis and psor...

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Bibliografiske detaljer
Udgivet i:Science
Main Authors: Reynolds, Gary, Vegh, Peter, Fletcher, James, Poyner, Elizabeth F.M., Stephenson, Emily, Goh, Issac, Botting, Rachel A., Huang, Ni, Olabi, Bayanne, Dubois, Anna, Dixon, David, Green, Kile, Maunder, Daniel, Engelbert, Justin, Efremova, Mirjana, Polański, Krzysztof, Jardine, Laura, Jones, Claire, Ness, Thomas, Horsfall, Dave, McGrath, Jim, Carey, Christopher, Dorin-Mirel, Popescu, Webb, Simone, Xiao-nong, Wang, Sayer, Ben, Jong-Eun, Park, Negri, Victor A., Belokhvostova, Daria, Lynch, Magnus, McDonald, David, Filby, Andrew, Hagai, Tzachi, Meyer, Kerstin B., Husain, Akhtar, Coxhead, Jonathan, Vento-Tormo, Roser, Behjati, Sam, Lisgo, Steven, Alexandra-Chloé, Villani, Bacardit, Jaume, Jones, Phil, O’Toole, Edel A., Ogg, Graham S., Rajan, Neil, Reynolds, Nick J., Teichmann, Sarah A., Watt, Fiona, Haniffa, Muzlifah
Format: Artigo
Sprog:Inglês
Udgivet: 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611557/
https://ncbi.nlm.nih.gov/pubmed/33479125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aba6500
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